AlphaGem Bio's launches new injection molded PCR plates

AlphaGem Bio, a supplier of medical labware for liquid transfer handling, has launched a polymerase chain reaction (PCR) plate made of TOPAS cyclic olefin copolymer (COC) from Polyplastics USA. The new plate for genomic testing provides greater rigidity and heat stability compared with plastics such as polypropylene (PP) and polycarbonate (PC). 

The new injection molded PCR plates are particularly suited for larger laboratories that use robotic handling for high-volume applications, according to Dale Taunk, president of AlphaGem Bio. “The use of cyclic olefin copolymer enables us to expand our product offering with a higher performing option that meets automation needs,” said Taunk. 

The new PCR product, a 96-well SBS standard microplate, is made of TOPAS medical grade resin. TOPAS COC’s heat stability meets the requirements for thermal cycling up to 100 °C. In addition, COC is more rigid than PP, which allows for use in robotic handling applications. The material’s high optical properties (92% clarity) facilitate reliable laser testing and real-time visual observation. 

The high-flow characteristics of TOPAS COC enable extensive detail to be designed into PCR plates and other diagnostic and microfluidic disposable components. Well counts can be maximized, flow channels incorporated, and analyses optimized.

Due to its ultra-high purity, TOPAS COC has lower leachables and extractables than competing materials, resulting in the most reliable and repeatable results. The inert nature of the medical-grade plastic prevents interference with reactions and analyses, further enhancing precision. Other important features of TOPAS COC polymer include excellent UV transparency and low birefringence.